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Semester III

Principles of Genetics

GPB 211 · 3 (2+1) credit hours

Syllabus

Topic-wise syllabus

Theory

28 topics · 30 lectures

Theory topics
No.TopicLectures
Unit I
1Pre and Post Mendelian concepts of heredity1
2Mendelian principles of heredity1
3Study of model organisms (Drosophila, Arabidopsis, Garden pea, E. coli, and mice)1
4Architecture of chromosomes, chromonemata, chromosome matrix, chromomeres, centromere, secondary constriction and telomere1
5Special types of chromosomes1
6Chromosomal theory of inheritance1
7Cell cycle and Cell division – mitosis & meiosis1
8Probability and Chi-square1
9Dominance relationships1
10Epistatic interactions with examples (complementary, supplementary, duplicate gene interactions)1
11Epistatic interactions with examples (masking, inhibitory, polymeric and additive gene interactions)1
Unit II
12Introduction and definition of cytology, genetics and cytogenetics and their interrelation1
13Multiple alleles, pleiotropism and pseudoalleles1
14Sex determination and sex linkage1
15Sex limited and sex influenced traits1
16Blood group genetics1
17Linkage and its estimation1
18Crossing over mechanism1
19Chromosome mapping1
20Structural variations in chromosomes and their implications1
21Numerical variations in chromosomes and their implications1
Unit III
22Use of haploids, dihaploids and double haploids in Genetics1
23Mutation, classification, Methods of inducing mutations, mutagenic agents and induction of mutation2
24Qualitative & Quantitative traits, Polygenes and continuous variations and Multiple factor hypothesis1
25Cytoplasmic inheritance1
26Types of DNA and RNA, Nature, structure and replication of genetic material2
27Transcription and translation mechanism of genetic material1
28Gene concept: Gene structure and function and regulation1

Practical

9 topics

Practical topics
No.Topic
1Study of microscope: parts and types
2Study of cell structure
3Mitosis and Meiosis cell division
4Experiments on monohybrid, dihybrid, trihybrid, test cross and back cross
5Experiments on epistatic interactions including test cross and back cross
6Experiments on Chi-square test and probability
7Determination of linkage and cross over analysis (through two-point test cross and three-point test cross data)
8Study on sex-linked inheritance in Drosophila
9Study of models on DNA and RNA structure

Study material

Notes

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